Endocrine Abstracts

Introduction: Low-grade pituitary gliomas are extremely rare neoplasms, originating from the pituicytes of the posterior pituitary or infundibulum. The incidence of these tumors increases with age and peaks in the seventh decade of life. Gliomas are primary brain tumors of the supporting glial cells of the central nervous system, which derive from neuroglial stem cells or progenitor cells. They are responsible for nearly 30% of all primary brain tumors and 80% of all malignant...

Introduction: Myxedematous coma is a rare endocrine emergency that settles in the absence of appropriate treatment for hypothyroidism for a long period. The severe and chronic reduction of serum thyroid hormones culminates in the insufficiency of compensatory mechanisms that maintain the physiological homeostasis of the organism. The clinical condition is severe, commonly associated with hypoxemia, hypercapnia, hypothermia, reduced cardiac output, and altered mental status.</p...

Introduction: The treatment of thyroid diseases with thionamides can cause agranulocytosis a potentially fatal side effect. The manifestations resulting from such a condition include, in most cases, infections that, if not treated immediately, have a high risk of septicemia. Therefore, the clinical presentation includes fever of unknown origin and infections such as pneumonia, tonsillitis, and abscesses. Most patients who do not receive immediate medical intervention progress ...

Introduction: Primary hypobetalipoproteinemia corresponds to a series of congenital disorders that have a variable incidence from 3.2% to less than 1 in 1 million, depending on the type of genetic mutation. The diseases that comprise it occur due to different types of mutations in genes that will encode important proteins at different stages of lipid metabolism. Individuals with determinant mutations of severe phenotypes, such as Bassen-Kornzweig syndrome, as known as Abetalip...